A Journey, Not a Destination

Dialysis: destination or journey.

The continued poor survival and diminished quality of life for patients treated with dialysis, particularly elderly individuals, is an important health care issue. In this issue of JASN, Vandecasteele and Kurella Tamura propose a change from a process-driven approach to dialysis care to one that incorporates a realistic assessment, in collaboration with the patient, of the relationship between ...

Nanomedicine: destination or journey?

Nanomedicine in a broad sense is the application of nano-scale technologies to the practice of medicine. The creation of nanodevices such as nanobots capable of performing therapeutic functions in vivo is a destination within the emerging field of nanomedicine. On the journey to that destination, significant technological advances across multiple scientific disciplines continue to be proposed, ...

Improving surgical outcomes: it is the destination not the journey

Studies have demonstrated that optimising the circulating volume reduces morbidity after major surgery. This optimisation is usually achieved through maximisation of the stroke volume guided by oesophageal Doppler. New monitoring parameters of preload responsiveness using information from the arterial trace are now showing some promise in achieving the same goal. The present commentary examines...

Performance measures: the destination or the journey?

It's about the journey, Not the destination: The birth of radioimmunoassay. 1960.

Featured Article: Yalow RS, Berson SA. Immunoassay of endogenous plasma insulin in man. J Clin Invest 1960;39:1157–75. They met in 1950. She was a 29-year-old researcher with a PhD in nuclear physics who had been accepted to graduate school only because there was a shortage of male students because of World War II. He was a 32-year-old physician who had collected more than 100 rejection letters...